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BCG The only tuberculosis Vaccine

October 3, 2008 by dadmin

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The vaccine known as BCG, or Bacille Calmette-Guérin, is officially defined as a living culture of an attenuated form of Mycobacterium bovis, an organism similar to Mycobacterium tuberculosis which is the leading cause of tuberculosis in humans. The vaccine was developed at the turn of the 20th century as part of an attempt to halt the spread of tuberculosis in European industrial cities.

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Alternatives to Protein Biologics

October 3, 2008 by vikas

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It should be noted that there may be alternative drugs to those biological materials produced by gene manipulation and expression. This will be especially relevant if the high cost of bioengineered compounds becomes unacceptable to society as a whole. The point is that proteins may have unique biological activities that can be mimicked in some cases by small molecular weight compounds, in other words, conventional drugs. At present there are few examples of this type of activity but research has already been initiated—and, who knows, this may have a successful outcome.

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Generic Biotechnological Drug Issues

October 3, 2008 by vikas

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The respected scientific journalist W. Wayt Gibbs, writing in Scientific American (2003), has suggested that many of the issues associated with concerns about the high costs of individual bioengineered protein drugs will go away when the patents lapse and generic drug manufacturers become involved.

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Classification of Protiens

October 1, 2008 by vikas

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Proteins are often put into one of two categories, globular or fibrous, on the basis of their overall structure. Globular proteins have compactly folded structures and tend to resemble globes or spheroids in overall shape.

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Short Tandem Repeats

September 21, 2008 by dadmin

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A short tandem repeat (STR) in DNA is a class of polymorphisms that occurs when a pattern of two or more nucleotides are repeated and the repeated sequences are directly adjacent to each other. The pattern can range in length from 2 to 10 base pairs (bp) (for example (CATG)n in a genomic region) and is typically in the non-coding intron region, making it junk DNA.

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Ebook Microbial Biotechnology

September 19, 2008 by craig

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Microbial Biotechnology: Fundamentals of Applied Microbiology
by Alexander N. Glazer (Author), Hiroshi Nikaido (Author)


Book Description

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