Category: biotech issues
On September 11, 2008, FDA learned that melamine may be contained in an infant formula manufactured by a firm in China. As of September 21, 2008, FDA learned that a total of 52,857 cases of nephrolithiasis (and, in some instances, renal failure) had been reported in China linked to consumption of this contaminated powdered formula.
Biotechnology offered the hope of cheaper and better drugs. Analysis of biotech products licensed in Europe shows the reality is somewhat different
To answer your first question: the three Ps in the title stand for people, profit and preservation. I must admit that when I was asked to participate in a discussion on 'The Biotechnology Industry and the Environment' at the recent BioVision conference in Lyon, France, I did not immediately think of the three Ps.
It should be noted that there may be alternative drugs to those biological materials produced by gene manipulation and expression. This will be especially relevant if the high cost of bioengineered compounds becomes unacceptable to society as a whole. The point is that proteins may have unique biological activities that can be mimicked in some cases by small molecular weight compounds, in other words, conventional drugs. At present there are few examples of this type of activity but research has already been initiated—and, who knows, this may have a successful outcome.
The respected scientific journalist W. Wayt Gibbs, writing in Scientific American (2003), has suggested that many of the issues associated with concerns about the high costs of individual bioengineered protein drugs will go away when the patents lapse and generic drug manufacturers become involved.
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